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Tomas Majtan Selected Research

Ligands

1/2016Targeting Cystathionine Beta-Synthase Misfolding in Homocystinuria by Small Ligands: State of the Art and Future Directions.
1/2013Human cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM.

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Tomas Majtan Research Topics

Disease

21Homocystinuria
09/2020 - 05/2010
2Hypermethioninemia
09/2020 - 01/2020
2Hyperhomocysteinemia
09/2020 - 01/2020
2Inborn Genetic Diseases (Disease, Hereditary)
01/2013 - 05/2010
1Down Syndrome (Down's Syndrome)
01/2022
1Stroke (Strokes)
01/2020
1Liver Diseases (Liver Disease)
01/2020
1Thrombosis (Thrombus)
01/2020
1Vascular Diseases (Vascular Disease)
01/2020
1Hemorrhage
01/2020
1Propionic Acidemia
01/2018
1Osteoporosis
12/2017
1Perinatal Death
12/2017
1Metabolic Diseases (Metabolic Disease)
01/2016
1Wounds and Injuries (Trauma)
09/2013
1Inflammation (Inflammations)
09/2013

Drug/Important Bio-Agent (IBA)

8Cystathionine beta-Synthase (Serine Sulfhydrase)IBA
06/2020 - 05/2010
8HomocysteineIBA
01/2020 - 09/2014
7Sulfur Amino AcidsIBA
01/2018 - 11/2012
6CystathionineIBA
01/2022 - 12/2012
4Proteins (Proteins, Gene)FDA Link
09/2020 - 04/2012
4EnzymesIBA
06/2020 - 01/2016
3Methionine (L-Methionine)FDA Link
09/2020 - 01/2016
3Cysteine (L-Cysteine)FDA Link
12/2017 - 01/2016
2SulfurIBA
06/2020 - 10/2013
2S-Adenosylmethionine (Ademetionine)IBA
01/2018 - 07/2016
2LigandsIBA
01/2016 - 01/2013
1Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2022
1Betaine (C.B.B.)FDA Link
09/2020
1Propionyl-Coenzyme A Carboxylase (Propionyl CoA Carboxylase)IBA
01/2018
1FlavonoidsIBA
09/2013
1Peptide Hydrolases (Proteases)FDA Link
09/2013
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
09/2013
1Pyridoxine (Pyridoxin)FDA LinkGeneric
05/2010

Therapy/Procedure

6Enzyme Replacement Therapy
01/2020 - 01/2016
3Enzyme Therapy
09/2020 - 01/2020
2Therapeutics
01/2020 - 07/2016